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KMID : 0525720080130040219
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Journal of Chitin and Chitosan
2008 Volume.13 No. 4 p.219 ~ p.224
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Effect of the Antimicrobial Activity of Maleic Acid-g-Chitosan Copolymer
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Kim Ji-Min
Chung Suk-Jin
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Abstract
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Water-soluble Chitosans, CsMa, were prepared by grafting maleic acid on an amino group of chitosan, and identified the structure of grafted chitosan using H-NMR and FT-IR. The chitosan derivatives were used to improve the solubility of chitosan in water. The deacetylation degree of the chitosan was 99.3%. The viscosity-average molecular weights were 6.72 × 10, 1.27 × 10, respectively. The antibacterial effects with the concentration of CsMa for Staphylococcus aureus, Streptococcus pyogenes, and Escherichia coli were 93% at 500 ppm, 94.6% at 300 ppm, and 93% at 300ppm, respectively. The Antimicrobial effect at 300 ppm of CsMa concentration was 100% for Staphylococcus aureus, 98.3% for Streptococcus pyogenes, and 96.7% for Escherichia coli.; 100% at 500 ppm for three kinds of mentioned above.
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KEYWORD
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Chitin, Chitosan, Chitosan derivatives, Antimicrobial activity, Staphylococcus aureus, Streptococcus pyogenes, Escherichia coli
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